Sam Darnold To Start Against Rams, Brock Purdy To Be Rested

San Francisco 49ers head coach Kyle Shanahan said that quarterback Brock Purdy will not play in the Week 18 regular season finale against the Los Angeles Rams on Sunday. As a result, Sam Darnold will make his first start of the season in a meaningless game for the Niners, as they are already locked into the top seed in the NFC and will have a first-round bye in the playoffs. In addition to Purdy, the Niners ruled out star running back Christian McCaffrey (calf) already after he strained his calf in the Week 17 win over the Washington Commanders. San Francisco could choose to limit other key offensive weapons this weekend, making all Niners players risky in fantasy lineups in Week 18. Darnold will be in play as a low-end QB2 option for fantasy managers in leagues that start two QBs.